Pathogenesis: understanding the disease: Outbreak - how cancer spreads

Research must specifically focus on breast cancer tumor and stromal biology, including: (1) studies of relevant proteins and genes with an emphasis on their relationship to the actual disease, and (2) elucidating key cell signaling, growth control, cell c


The Role of Twist1 in Epithelial-mesenchymal Transition 2010 (Cycle 16)
  University of California, San Diego   $90,000
  Award Type: Postdoctoral Fellowship
 
The Role of Clim Proteins in Breast Cancer 2010 (Cycle 16)
  University of California, Irvine   $90,000
  Award Type: Postdoctoral Fellowship
 
The Role of microRNAs in Triple-Negative Breast Cancer 2010 (Cycle 16)
  University of California, San Francisco   $90,000
  Award Type: Postdoctoral Fellowship
 
Myeloperoxidase Mediated Protection in Breast Cancer 2010 (Cycle 16)
  The Burnham Institute for Medical Research   $286,500
  Award Type: IDEA
 
Local Adipocyte Function in Breast Cancer 2010 (Cycle 16)
  Torrey Pines Institute for Molecular Studies   $273,000
  Award Type: IDEA
 
p97 as a Therapeutic Target in Breast Cancer Metastasis 2010 (Cycle 16)
  Proteomics Research Institute for Systems Medicine   $292,500
  Award Type: IDEA
 
Inhibiting Mutation to Prevent and Treat Breast Cancer 2010 (Cycle 16)
  Scripps Research Institute   $187,438
  Award Type: IDEA
 
Reelin Signaling Involvement in Breast Cancer Cell Migration 2010 (Cycle 16)
  University of California, Los Angeles   $149,493
  Award Type: IDEA
 
Complement-mediated Stem Cell Recruitment to Breast Cancer 2010 (Cycle 16)
  Torrey Pines Institute for Molecular Studies   $136,500
  Award Type: IDEA
 
A Molecular Strategy to Inhibit Breast Cancer Metastasis 2009 (Cycle 15)
  University of California, San Francisco   $150,000
  Award Type: IDEA
 
P32: New Functional Target in Breast Cancer Brain Metastasis 2009 (Cycle 15)
  Scripps Research Institute   $90,000
  Award Type: Postdoctoral Fellowship
 
Substrate Profiling of Breast Cancer Related Proteases 2009 (Cycle 15)
  Scripps Research Institute   $76,000
  Award Type: Dissertation
 
Breast Cancer Tumor-Stroma Interactions in an In Vivo Model 2009 (Cycle 15)
  Vaccine Research Institute of San Diego   $284,250
  Award Type: IDEA
 
Proline Metabolism in Metastatic Breast Cancer 2009 (Cycle 15)
  The Burnham Institute for Medical Research   $284,895
  Award Type: IDEA
 
Stroma Expression Patterns in Breast Cancer 2009 (Cycle 15)
  Palo Alto Institute for Research & Education   $352,500
  Award Type: IDEA-competitive renewal
 
Global Analysis of Protein Ubiquitination in Breast Cancer 2008 (Cycle 14)
  The Burnham Institute for Medical Research   $90,000
  Award Type: Postdoctoral Fellowship
 
Dietary Metabolite Inhibition of Breast Cancer Cell Survival 2008 (Cycle 14)
  University of California, Berkeley   $76,000
  Award Type: Dissertation
 
Dissecting the Role of Twist in Breast Cancer Metastasis 2008 (Cycle 14)
  University of California, San Diego   $76,000
  Award Type: Dissertation
 
Chemokine Receptor Signaling in Breast Cancer 2008 (Cycle 14)
  University of California, San Diego   $74,660
  Award Type: Dissertation
 
Nanolipoproteins to Study Breast Cancer Growth Receptors 2008 (Cycle 14)
  University of California, Davis   $63,234
  Award Type: IDEA
 
Global Analysis of Protein Ubiquitination in Breast Cancer 2008 (Cycle 14)
  Sidney Kimmel Cancer Center   $45,000
  Award Type: Postdoctoral Fellowship
 
Maternal Embryonic Leucine Zipper Kinase in Mammary Tumors 2008 (Cycle 14)
  The Burnham Institute for Medical Research   $286,500
  Award Type: IDEA
 
Role of Estrogen-modulated Protein AGR2 in Breast Cancer 2008 (Cycle 14)
  University of California, Irvine   $71,491
  Award Type: Dissertation
 
Tumor Suppressor 14-3-3sigma in Breast Cancer Progression 2008 (Cycle 14)
  Lawrence Berkeley National Laboratory   $63,334
  Award Type: Dissertation
 
Breast Tumor Responses to Novel TGF-beta Inhibitors 2007 (Cycle 13)
  University of California, San Francisco   $60,521
  Award Type: Postdoctoral Fellowship
 
Trask, a Candidate Breast Cancer Metastasis Protein 2007 (Cycle 13)
  University of California, San Francisco   $90,000
  Award Type: Postdoctoral Fellowship
 
Targeting Tissue Factor in Breast Cancer 2007 (Cycle 13)
  Scripps Research Institute   $89,600
  Award Type: Postdoctoral Fellowship
 
Identification of Metastasis Competent Breast Cancer Cells 2006 (Cycle 12)
  Sidney Kimmel Cancer Center   $59,805
  Award Type: IDEA
 
The Role of Serine and Metallo-Hydrolases in Breast Cancer 2006 (Cycle 12)
  Scripps Research Institute   $72,275
  Award Type: Dissertation
 
Identification of Metastasis Competent Breast Cancer Cells 2006 (Cycle 12)
  La Jolla Institute for Molecular Medicine   $267,567
  Award Type: IDEA
 
Twist Activation in Breast Cancer Metastasis 2006 (Cycle 12)
  University of California, San Diego   $150,000
  Award Type: IDEA
 
The Role of Podosomes in Breast Cancer Metastasis 2006 (Cycle 12)
  The Burnham Institute for Medical Research   $134,618
  Award Type: Postdoctoral Fellowship
 
Survivin: Target for Breast Cancer Brain Metastases 2005 (Cycle 11)
  University of Southern California   $242,854
  Award Type: IDEA
 
Novel Approach to Analyze Estrogen Action in Breast Cancer 2005 (Cycle 11)
  La Jolla Institute for Molecular Medicine   $310,950
  Award Type: IDEA
 
Imaging RhoC-induced Breast Cancer Invasion and Angiogenesis 2005 (Cycle 11)
  Scripps Research Institute   $15,725
  Award Type: Postdoctoral Fellowship
 
Role of Integrins in Lymphangiogenesis During Breast Cancer 2005 (Cycle 11)
  University of California, San Diego   $134,530
  Award Type: Postdoctoral Fellowship
 
Integrated Proteomic and Metabolic Analysis of Breast Cancer 2005 (Cycle 11)
  Scripps Research Institute   $59,121
  Award Type: Dissertation
 
Identifying Metastatic Breast Cells from Peripheral Blood 2005 (Cycle 11)
  Lawrence Livermore National Laboratory   $490,774
  Award Type: IDEA-competitive renewal
 
Imaging RhoC-induced Breast Cancer Invasion and Angiogenesis 2005 (Cycle 11)
  University of California, San Diego   $119,220
  Award Type: Postdoctoral Fellowship
 
Characterizing Breast Cancer Cells in Blood and Bone Marrow 2004 (Cycle 10)
  Stanford University   $155,781
  Award Type: IDEA
 
Identifying Metastatic Breast Cells from Peripheral Blood 2004 (Cycle 10)
  Lawrence Livermore National Laboratory   $203,223
  Award Type: IDEA
 
Hox Transcriptional Regulation of Breast Tumor Angiogenesis 2004 (Cycle 10)
  University of California, San Francisco   $30,890
  Award Type: Postdoctoral Fellowship
 
Profiling Enzyme Activities in Human Breast Cancer 2004 (Cycle 10)
  Scripps Research Institute   $464,906
  Award Type: TRC Full
 
Profiling Enzyme Activities in Human Breast Cancer 2004 (Cycle 10)
  Stanford University   $400,000
  Award Type: TRC Full
 
Stem Cells in Breast Cancer Metastasis 2004 (Cycle 10)
  Scripps Research Institute   $621,289
  Award Type: SPRC Full
 
Stem Cells in Breast Cancer Metastasis 2004 (Cycle 10)
  The Burnham Institute for Medical Research   $313,559
  Award Type: SPRC Full
 
A Novel Predictive Test for Her-2/EGFR Ab-based Therapeutics 2003 (Cycle IX)
  University of California, San Francisco   $79,600
  Award Type: Postdoctoral Fellowship
 
Angiogenesis in Hyperplasia to In-Situ Breast Cancers 2003 (Cycle IX)
  University of California, Irvine   $250,000
  Award Type: STEP
 
Activity Based Profiling of Breast Cancer Xenografts 2003 (Cycle IX)
  Scripps Research Institute   $30,000
  Award Type: Dissertation
 
HOX Transcriptional Regulation of Angiogenesis 2002 (Cycle VIII)
  University of California, San Francisco   $39,029
  Award Type: Postdoctoral Fellowship
 
Method to Profile Active Metalloproteases in Breast Cancer 2002 (Cycle VIII)
  Scripps Research Institute   $85,576
  Award Type: Postdoctoral Fellowship
 
The Role of Matrix Metalloproteinase 13 in Breast Cancer 2002 (Cycle VIII)
  University of California, San Francisco   $80,000
  Award Type: Postdoctoral Fellowship
 
Identifying Accessible Targets in Human Breast Tumors 2002 (Cycle VIII)
  Sidney Kimmel Cancer Center   $480,843
  Award Type: STEP
 
Trypsin-like Proteases as Metastatic Agents in Breast Cancer 2001 (Cycle VII)
  University of California, Riverside   $295,893
  Award Type: New Investigator
 
Novel Enzymes Associated with Breast Cancer Angiogensis 2001 (Cycle VII)
  University of California, San Francisco   $100,000
  Award Type: IDEA
 
Lasp-1 Signaling in Breast Carcinoma Cell Invasion/Migration 2001 (Cycle VII)
  Scripps Research Institute   $85,508
  Award Type: Postdoctoral Fellowship
 
Smoking Effect on Pulmonary Metastasis from Breast Cancer 2001 (Cycle VII)
  University of California, Davis   $74,968
  Award Type: IDEA
 
TGF-B3 and small GTPases in Invasive Breast Cancer 2000 (Cycle VI)
  Childrens Hospital, Los Angeles   $323,925
  Award Type: New Investigator
 
Role of MMPs in Breast Tumor Initiation and Aggressiveness 2000 (Cycle VI)
  Lawrence Berkeley National Laboratory   $75,422
  Award Type: Postdoctoral Fellowship
 
Analysis of Genes Predictive of Breast Cancer Metastasis 2000 (Cycle VI)
  University of California, Davis   $221,925
  Award Type: New Investigator
 
The Role of IL-8 and its Receptors in Angiogenesis 2000 (Cycle VI)
  La Jolla Institute for Molecular Medicine   $149,699
  Award Type: IDEAS II
 
Profiling Serine Protease Activities in Breast Cancer 2000 (Cycle VI)
  Scripps Research Institute   $265,950
  Award Type: IDEAS II
 
Identifying Breast Cancer Targets for Protease Inhibitors 2000 (Cycle VI)
  Scripps Research Institute   $42,120
  Award Type: Postdoctoral Fellowship
 
Cell Adhesion and Drug Resistance in Breast Cancer 2000 (Cycle VI)
  The Burnham Institute for Medical Research   $190,773
  Award Type: IDEAS II
 
Tumor Suppression by Dystrogylcan in Breast Epithelial Cells 2000 (Cycle VI)
  Lawrence Berkeley National Laboratory   $181,347
  Award Type: New Investigator
 
Analysis of Angiogenic Pathways in Metastatic Breast Cancer 2000 (Cycle VI)
  The Burnham Institute for Medical Research   $86,400
  Award Type: Postdoctoral Fellowship
 
Breast Cancer Cell Binding to the Endothelium 1999 (Cycle V)
  Scripps Research Institute   $326,892
  Award Type: IDEAS II
 
The Shp-2 Tyrosine Phosphatase in Breast Tumor Migration 1999 (Cycle V)
  The Burnham Institute for Medical Research   $75,600
  Award Type: Postdoctoral Fellowship
 
How Does Endostatin Inhibit Breast Cancer Angiogenesis? 1999 (Cycle V)
  The Burnham Institute for Medical Research   $292,535
  Award Type: IDEAS II
 
Targeting Breast Cancer Blood Vessels 1999 (Cycle V)
  Sidney Kimmel Cancer Center   $363,905
  Award Type: IDEAS II
 
Role of Chemokine Receptors in Breast Cancer Metastasis 1999 (Cycle V)
  University of California, Los Angeles   $41,311
  Award Type: IDEA
 
A New Model for Inflammatory Breast Carcinoma 1999 (Cycle V)
  University of California, Los Angeles   $200,000
  Award Type: IDEAS II
 
Spatial Control of Matrix Proteolysis in Breast Cancer 1999 (Cycle V)
  The Burnham Institute for Medical Research   $340,383
  Award Type: IDEAS II
 
Spatial Control of Matrix Proteolysis in Breast Cancer 1999 (Cycle V)
  La Jolla Institute for Molecular Medicine   $0
  Award Type: IDEAS II
 
Cell Adhesion Signaling Defects in Breast Cancer 1998 (Cycle IV)
  The Burnham Institute for Medical Research   $26,841
  Award Type: Postdoctoral Fellowship
 
Intracellular Signaling by PI3K in Breast Cancer Metastasis 1998 (Cycle IV)
  University of California, Davis   $43,329
  Award Type: IDEA
 
Role of Gamma-catenin in a Breast Cancer Mouse Model 1998 (Cycle IV)
  The Burnham Institute for Medical Research   $290,363
  Award Type: IDEAS II
 
Leukocyte Recruitment, Angiogenesis and Breast Cancer 1998 (Cycle IV)
  La Jolla Institute for Molecular Medicine   $304,797
  Award Type: IDEAS II
 
Understanding Breast Cancer Cell Metastasis to Bone 1998 (Cycle IV)
  The Burnham Institute for Medical Research   $436,722
  Award Type: New Investigator
 
Integrin Activation in the Metastasis of Breast Cancer 1997 (Cycle III)
  The Burnham Institute for Medical Research   $264
  Award Type: Postdoctoral Fellowship
 
Integrin Receptor Activation in Breast Cancer 1997 (Cycle III)
  Scripps Research Institute   $71,564
  Award Type: Postdoctoral Fellowship
 
Novel Breast Cancer Epithelial Cell Metalloproteinase 1997 (Cycle III)
  California Pacific Medical Center Research Institute   $193,995
  Award Type: IDEA
 
Zinc Finger proteins as therapeutic agents for breast 1996 (Cycle II)
  Scripps Research Institute   $43,440
  Award Type: Postdoctoral Fellowship
 
Why do 70% of Breast Cancers Metastasize to Bone? 1996 (Cycle II)
  The Burnham Institute for Medical Research   $97,407
  Award Type: IDEA
 
IGF-II and cathespin D in tumor growth and metastasis 1996 (Cycle II)
  Loma Linda University   $353,776
  Award Type: New Investigator
 
How are Collagenses Involved in Breast Cancer Metastasis? 1996 (Cycle II)
  La Jolla Institute for Molecular Medicine   $584,513
  Award Type: Research Project
 
Abnormal Regulation in Breast Cancer Development/Metastasis 1996 (Cycle II)
  Scripps Research Institute   $516,413
  Award Type: Research Project
 
HSP27 Regulation of Breast Tumor Blood Vessel Growth 1995 (Cycle I)
  Scripps Research Institute   $75,570
  Award Type: Postdoctoral Fellowship
 
Cell Microenvironment and Progression of Breast Cancer 1995 (Cycle I)
  Lawrence Berkeley National Laboratory   $66,048
  Award Type: Postdoctoral Fellowship
 
The Invasive Nature of Epithelial Breast Cancer Cells 1995 (Cycle I)
  California Pacific Medical Center Research Institute   $269,852
  Award Type: New Investigator
 
The Breast Tumor Suppressor Function of Hyaluronidase 1995 (Cycle I)
  University of California, San Francisco   $302,120
  Award Type: Research Project
 
Prevention of Breast Cancer by Blocking Integrin Function 1995 (Cycle I)
  The Burnham Institute for Medical Research   $545,057
  Award Type: Research Project
 
The Invasive Nature of Epithelial Breast Cancer Cells 1995 (Cycle I)
  Lawrence Berkeley National Laboratory   $105,837
  Award Type: New Investigator